AP214 ameliorates sepsis-induced acute kidney injury and mor(14)

NIH-PA Author Manuscript

NIH-PA Author Manuscript

NIH-PA Author ManuscriptFigure 4. Effect of AP214 on liver damage induced by CLPSerum aspartate transaminase (AST) and alanine transaminase (ALT) were measured 18 hrafter lethal CLP surgery. AP214 was injected at 0 and 6 hr (A, B) or only at 6 hr (delayed-treatment) (C). Values are mean ± SEM (n = 5 in sham-operated group, n = 14 in CLP group,n = 7 in AP214 group). #, P < 0.05 vs. CLP.