AP214 ameliorates sepsis-induced acute kidney injury and mor(16)

NIH-PA Author Manuscript

NIH-PA Author Manuscript

NIH-PA Author ManuscriptFigure 6. AP214 reduced serum TNF-α and IL-10

Serum TNF-α and IL-10 levels were measured by ELISA. AP214 was injected at 0 and 6 hr(A, B) or only at 6 hr (delayed-treatment) (C, D). Animals were sacrificed 18 hr after lethalCLP surgery. Values are mean ± SEM (n = 5 in sham-operated group, n = 14 in CLP group, n= 7 in each AP214 group). #, P < 0.05 vs. CLP.