第二掣蹶大学硕士学位论文多层螺旋CT蝌脏灌注抟初步研究
StudyofHepaticPerfusionwith
AbstractMulti—sliceSpiralCT
Objective:Toresearchthescantechniqueofhepaticpeffusionwithmulti—slicespiralCTandit’Svalueinthediagnosisanddifferentialdiagnosisofliverdiseases.Methods:FromJune2002tOFebruary2003,88patients(53
femalelunderwentdynamicCTofmeliverwereselected
agewasmale,35tOottrstudyMeaninto48(22to75)。60volunteers谢出。波hepaticdisorderweredivided3groupsaccording幻the
7ml/sinjected17casesspeedofcontrastmedium(4ml/s,5ml/s,respectively).Ofthewithcirrhosis,9weremild,8weremuchsevere.11patientssufferedfromhepaticcancer,Theyallhavenormalcardiacfunction。Aproperslicewasselectedafterconventionalabdominal
repeatedlyscannedscanandUS堍aSomatomPlus4VolumeZoomscanner.40images
awereacquiredwith0.5一seescanningtimeand
ofconWasta2-seeintervalwithinto0~80-secafterbolusinjectionmedium.Patientswereasked
融蘸smoothly.Aregionofinterest(RODof氇eaorta,spleenandliverWaS
curvedrawn,andCTvaluesoftheseROIsweremeasuredtogettime-density
(TDC),andperfusionvNuewerecalculatedoutwithfollowingformulas.Hepaticarterial
splemcperfusion(HAP)=peakgradientoftheliverTDCbeforethepeak/peakaortaenhancement;Hepaticportalperfusion(}卿)=peak
aortagradientoftheliverTDCafterthesplemcpeak/peak
liverenhancement;Totalperfusion(TLP)一}认P+}丑叩;Hepaticarterialperfusionindex(}巾I)=
Results:1。HAP/TLP;Hepaticportalperfusion
Althoughthereis
tOnoindex(PPI)=HPWlLRsignificantdifferenceofallindexeswhencompared4ml/sto7ml/sgroup,thedifference5ml/sgroup,and5ml/sbetween4ml/sand4