CERVUS3.0说明书(16)

parentage analysis program整理自软件help文件,下载过的朋友可以直接在help里查看。

Feedback

Your feedback is very important in helping to identify bugs and in the development of future versions of Cervus. Any comments, queries or suggestions for improvement will be gratefully received - please email .

If you have a question about how to use the program or interpret the results, first please look for the answer within these help pages. If you can't find the answer to your question then by all means send an email to the address above.

2.Genetic advice

How many loci are needed for successful parentage analysis? The number of marker loci required to resolve parentage with a given level of confidence depends on a number of factors. The four main factors are:

1. The number of candidate parents to be distinguished.

2. The proportion of candidate parents that are sampled.

3. Whether genetic data is available from a known parent (in maternity and paternity

analysis) or whether the sex of candidate parents is known (in parent pair analysis).

4. The expected heterozygosity of each locus.

The success of analysis is also dependent to a lesser extent on the quality of genetic data: the proportion of loci typed and the proportion of loci mistyped.

All of these factors may be explored with the Cervus simulation module using

observed allele frequencies, an imaginary set of alleles frequencies or a mixture of the two.

In large scale parentage analysis, there tend to be a proportion of parentage tests that cannot be resolved with a given set of loci because the offspring in question carry